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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>白介素1β抗體
      白介素1β抗體
      • 產品貨號:
        BN42204R
      • 中文名稱:
        白介素1β抗體
      • 英文名稱:
        Rabbit anti-IL-1 Beta Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN42204R-50ul

        50ul

        ¥1486.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Dog) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN42204R-100ul

        100ul

        ¥2360.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Dog) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN42204R-200ul

        200ul

        ¥3490.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Dog) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      產品描述

      英文名稱IL-1 Beta
      中文名稱白介素1β抗體
      別    名Catabolin; H1; IL-1β; Hematopoietin 1; IFN beta inducing factor; IL 1; IL 1 beta; IL 1B; IL1B; IL1F2; Interleukin 1 beta; Interleukin 1 beta precursor; LAF; OAF; Osteoclast activating factor; Preinterleukin beta; Pro interleukin 1 beta; IL1B_HUMAN; Interleukin-1 beta; IL-1 beta.  



      研究領域細胞生物  免疫學  生長因子和激素  糖蛋白  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Mouse, Rat,  (predicted: Human, Dog, Horse, Rabbit, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量17/32kDa
      細胞定位分泌型蛋白 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human IL-1 Beta:161-269/269 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

      Function:
      Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

      Subunit:
      Monomer.

      Subcellular Location:
      Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

      Similarity:
      Belongs to the IL-1 family.

      SWISS:
      P01584

      Gene ID:
      3553

      Database links:

      Entrez Gene: 3553 Human

      Entrez Gene: 16176 Mouse

      Entrez Gene: 24494 Rat

      Omim: 147720 Human

      SwissProt: P01584 Human

      SwissProt: P10749 Mouse

      SwissProt: Q63264 Rat

      Unigene: 126256 Human

      Unigene: 222830 Mouse

      Unigene: 9869 Rat




      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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