CD27重組兔單克隆抗體

產品貨號：

BN42161R
中文名稱：

CD27重組兔單克隆抗體
英文名稱：

Rabbit anti-CD27 Monoclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN42161R-50ul

50ul

￥2020.00

交叉反應：Mouse(predicted:Rat,Human) 推薦應用：WB,IHC-P,IHC-F,ICC
BN42161R-100ul

100ul

￥3240.00

交叉反應：Mouse(predicted:Rat,Human) 推薦應用：WB,IHC-P,IHC-F,ICC

產品描述

英文名稱	CD27
中文名稱	CD27重組兔單克隆抗體
別名	CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7.
研究領域	腫瘤免疫學干細胞淋巴細胞 t-淋巴細胞細胞因子
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	3C3
交叉反應	Mouse, (predicted: Human, Rat, )
產品應用	WB=1:500-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	55kDa
細胞定位	細胞膜
性狀	Lyophilized or Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human CD27:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產品介紹	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008] Function: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. Subunit: Homodimer. Interacts with SIVA1 and TRAF2. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Found in most T-lymphocytes. Post-translational modifications: Phosphorylated. O-glycosylated with core 1 or possibly core 8 glycans. Similarity: Contains 3 TNFR-Cys repeats. SWISS: P26842 Gene ID: 939 Database links: Entrez Gene: 939 Human Entrez Gene: 21940 Mouse Entrez Gene: 500318 Rat Omim: 186711 Human SwissProt: P26842 Human SwissProt: P41272 Mouse Unigene: 355307 Human Unigene: 367714 Mouse Unigene: 134200 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.