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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>ADAM17重組兔單克隆抗體
      ADAM17重組兔單克隆抗體
      • 產品貨號:
        BN42068R
      • 中文名稱:
        ADAM17重組兔單克隆抗體
      • 英文名稱:
        Rabbit anti-ADAM17 (9E7) Monoclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN42068R-50ul

        50ul

        ¥2020.00

        交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

      • BN42068R-100ul

        100ul

        ¥3240.00

        交叉反應:Human,Mouse(predicted:Rat) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

      產品描述

      英文名稱ADAM17 (9E7)
      中文名稱ADAM17重組兔單克隆抗體
      別    名A disintegrin and metalloproteinase domain 17; ADAM 17; ADAM metallopeptidase domain 17; ADAM17 protein; CD 156b; CD156b; CD156b antigen; CSVP; MGC71942; Snake venom like protease; TACE; TNF alpha convertase; TNF alpha converting enzyme; Tumor Necrosis Factor Alpha Converting Enzyme; A disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADA17_HUMAN.  
      研究領域腫瘤  免疫學  神經生物學  信號轉導  轉錄調節因子  
      抗體來源Rabbit
      克隆類型Monoclonal
      克 隆 號9E7
      交叉反應Human, Mouse,  (predicted: Rat, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:20-200 IHC-F=1:20-200 ICC=1:20-200 IF=1:20-200 (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量93kDa
      細胞定位細胞膜 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原Recombinant human ADAM17 protein:700-824/824 <Cytoplasmic>
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq].

      Subunit:
      Interacts with MAD2L1, MAPK14 and MUC1.

      Subcellular Location:
      Membrane.

      Tissue Specificity:
      Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.

      Similarity:
      Contains 1 disintegrin domain.
      Contains 1 peptidase M12B domain.

      SWISS:
      P78536

      Gene ID:
      6868

      Database links:

      Entrez Gene: 6868 Human

      Entrez Gene: 11491 Mouse

      Entrez Gene: 57027 Rat

      Omim: 603639 Human

      SwissProt: P78536 Human

      SwissProt: Q9Z0F8 Mouse

      SwissProt: Q9Z1K9 Rat

      Unigene: 404914 Human

      Unigene: 27681 Mouse

      Unigene: 144585 Rat



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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