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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>S腺苷L-同型半胱氨酸水解酶抗體
      S腺苷L-同型半胱氨酸水解酶抗體
      • 產品貨號:
        BN41919R
      • 中文名稱:
        S腺苷L-同型半胱氨酸水解酶抗體
      • 英文名稱:
        Rabbit anti-SAHH Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN41919R-50ul

        50ul

        ¥1486.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN41919R-100ul

        100ul

        ¥2360.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN41919R-200ul

        200ul

        ¥3490.00

        交叉反應:Rat,Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Dog,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      產品描述

      英文名稱SAHH
      中文名稱S腺苷L-同型半胱氨酸水解酶抗體
      別    名Adenosylhomocysteinase; AdoHcyase; ahcY; S adenosyl L homocysteine hydrolase; S adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; SAHH_HUMAN.  


      研究領域腫瘤  細胞生物  免疫學  信號轉導  轉錄調節因子  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量48kDa
      細胞定位細胞漿 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human SAHH:25-125/432 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

      Function:
      Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

      Subunit:
      Homotetramer.

      Subcellular Location:
      Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

      DISEASE:
      Defects in AHCY are the cause of hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) [MIM:613752]. A metabolic disorder characterized by hypermethioninemia associated with failure to thrive, mental and motor retardation, facial dysmorphism with abnormal hair and teeth, and myocardiopathy.

      Similarity:
      Belongs to the adenosylhomocysteinase family.

      SWISS:
      P23526

      Gene ID:
      191

      Database links:

      Entrez Gene: 191 Human

      Entrez Gene: 269378 Mouse

      Entrez Gene: 29443 Rat

      Omim: 180960 Human

      SwissProt: P23526 Human

      SwissProt: P50247 Mouse

      SwissProt: P10760 Rat

      Unigene: 388004 Human

      Unigene: 330692 Mouse

      Unigene: 371964 Mouse

      Unigene: 5878 Rat



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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