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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>胰島素樣生長因子1抗體
      胰島素樣生長因子1抗體
      • 產品貨號:
        BN41905R
      • 中文名稱:
        胰島素樣生長因子1抗體
      • 英文名稱:
        Rabbit anti-IGF I Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN41905R-50ul

        50ul

        ¥1486.00

        交叉反應:Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

      • BN41905R-100ul

        100ul

        ¥2360.00

        交叉反應:Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

      • BN41905R-200ul

        200ul

        ¥3490.00

        交叉反應:Human,Rat(predicted:Mouse,Dog,Pig,Cow,Rabbit,Sheep) 推薦應用:WB,IHC-P,IHC-F,IF,ELISA

      產品描述

      英文名稱IGF I
      中文名稱胰島素樣生長因子1抗體
      別    名IBP1; IGF 1; IGF I; IGF-1;IGF IA; IGF IB; IGF1; IGFI; IGFIA; Insulin like growth factor 1 (somatomedin C); Full=Insulin-like growth factor I; Insulin Like Growth Factor 1; Insulin like growth factor IA; Insulin like growth factor IB; Mechano growth factor; MGF; Mechano growth factor; MGF; Somatomedia C; Somatomedin C; IGF1_HUMAN.  
      研究領域細胞生物  發育生物學  信號轉導  生長因子和激素  糖尿病  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Rabbit, Sheep, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量7.7/21kDa
      細胞定位分泌型蛋白 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human IGF I:108-195/195 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]

      Function:
      The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.

      Subcellular Location:
      Secreted.

      DISEASE:
      Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1 deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation.

      Similarity:
      Belongs to the insulin family.

      SWISS:
      P05019

      Gene ID:
      3479

      Database links:

      Entrez Gene: 3479 Human

      Omim: 147440 Human

      SwissProt: P05019 Human

      Unigene: 160562 Human



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

      胰島素樣生長因子1(IGF-1)是一種生長調節激素,由肝分泌并入血液循環的中性多肽,具有調節生長和代謝、胰島素樣及促細胞分裂的活性。















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