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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>神經元特異性烯醇化酶/γ 烯醇化酶抗體
      神經元特異性烯醇化酶/γ 烯醇化酶抗體
      • 產品貨號:
        BN41629R
      • 中文名稱:
        神經元特異性烯醇化酶/γ 烯醇化酶抗體
      • 英文名稱:
        Rabbit anti-NSE Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN41629R-50ul

        50ul

        ¥1486.00

        交叉反應:Dog,Rat,Mouse,Human(predicted:Cow,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN41629R-100ul

        100ul

        ¥2360.00

        交叉反應:Dog,Rat,Mouse,Human(predicted:Cow,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      • BN41629R-200ul

        200ul

        ¥3490.00

        交叉反應:Dog,Rat,Mouse,Human(predicted:Cow,Chicken) 推薦應用:WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

      產品描述

      英文名稱NSE
      中文名稱神經元特異性烯醇化酶/γ 烯醇化酶抗體
      別    名Gamma-enolase; Gamma enolase; Neural enolase; Neuron specific enolase; neurone-specific enolase; 2 phospho D glycerate hydrolyase; Eno 2; Eno2; ENO2; ENOG; Enolase 2; Enolase 2 gamma neuronal; Enolase2; Neuron specific enolase; Neuron specific gamma enolase; NSE; ENOG_HUMAN; Gamma-enolase; 2-phospho-D-glycerate hydro-lyase; enolase 2, gamma, neuronal.  



      研究領域腫瘤  細胞生物  免疫學  神經生物學  腫瘤細胞生物標志物  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Human, Mouse, Rat, Dog,  (predicted: Chicken, Cow, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test  IF=1:100-500 (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量48kDa
      細胞定位細胞漿 細胞膜 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human NSE:201-300/434 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008].

      Function:
      Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.

      Subunit:
      Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific.

      Subcellular Location:
      Cytoplasm. Cell membrane. Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.

      Tissue Specificity:
      The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.

      Similarity:
      Belongs to the enolase family.

      SWISS:
      P09104

      Gene ID:
      2026

      Database links:

      Entrez Gene: 2026 Human

      Entrez Gene: 13807 Mouse

      Entrez Gene: 24334 Rat

      Omim: 131360 Human

      SwissProt: P09104 Human

      SwissProt: P17183 Mouse

      SwissProt: P07323 Rat

      Unigene: 511915 Human



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

      神經元特異性烯醇化酶(NSE)存在于神經元細胞和神經內分泌組織中,起源于神經內分泌細胞的腫瘤可產生過量的NSE。NSE也是小細胞肺癌的檢測指標,70%左右的小細胞肺癌患者血中NSE升高,而其他組織型肺癌NSE升高的患者僅為10%~20%。


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