雌激素受體相關蛋白α抗體

產品貨號：

BN41241R
中文名稱：

雌激素受體相關蛋白α抗體
英文名稱：

Rabbit anti-ERR-alpha Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41241R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41241R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱	ERR-alpha
中文名稱	雌激素受體相關蛋白α抗體
別名	Estrogen Related Receptor alpha; ERR-α; ERR α; ERRα; ERR alpha; Err 1; ERR a; ERR alpha; ERR-alpha; Err1; ERR1_HUMAN; ERRa; ERRalpha; ESRL 1; ESRL1; ESRR A; Esrra; Estrogen receptor like 1; Estrogen receptor related 1; Estrogen receptor-like 1; Estrogen related receptor alpha; Estrogen-related receptor alpha; Estrra; Nr3b1; Nuclear receptor subfamily 3 group B member 1; Steroid hormone receptor ERR1.
研究領域	腫瘤細胞生物染色質和核信號信號轉導生長因子和激素結合蛋白細胞骨架表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	47kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Estrogen Related Receptor alpha:101-200/423
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Subunit: Binds DNA as a monomer or a homodimer. Interacts (via the AF2 domain) with coactivator PPARGC1A (via the L3 motif); the interaction greatly enhances transriptional activity of genes involved in energy metabolism. Interacts with PIAS4; the interaction enhances sumoylation. Subcellular Location: Nucleus. Similarity: Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain. SWISS: P11474 Gene ID: 2101 Database links: Entrez Gene: 2101 Human Entrez Gene: 26379 Mouse Entrez Gene: 293701 Rat Omim: 601998 Human SwissProt: P11474 Human SwissProt: O08580 Mouse SwissProt: Q5QJV7 Rat Unigene: 110849 Human Unigene: 386776 Mouse Unigene: 130171 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.