Bcl-2結合抑凋亡蛋白2抗體

產品貨號：

BN41044R
中文名稱：

Bcl-2結合抑凋亡蛋白2抗體
英文名稱：

Rabbit anti-BAG2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41044R-100ul

100ul

￥2360.00

交叉反應：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41044R-200ul

200ul

￥3490.00

交叉反應：Human,Rat(predicted:Mouse,Dog,Pig,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產品描述

英文名稱	BAG2
中文名稱	Bcl-2結合抑凋亡蛋白2抗體
別名	BAG 2; BAG-2; BAG family molecular chaperone regulator 2; BAG-2; Bag2; BAG2_HUMAN; BCL 2 associated athanogene 2; Bcl-2-associated athanogene 2; BCL2 associated athanogene 2; dJ417I1.2; KIAA0576; MGC149462.
研究領域	腫瘤免疫學信號轉導細胞凋亡轉錄調節因子
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Rat, (predicted: Mouse, Dog, Pig, Cow, Horse, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=2ug/Test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	24kDa
細胞定位	細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human BAG2:151-211/211
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. Function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Similarity: Contains 1 BAG domain. SWISS: O95816 Gene ID: 9532 Database links: Entrez Gene: 9532 Human Omim: 603882 Human SwissProt: O95816 Human Unigene: 55220 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.