囊泡對接蛋白p115抗體

產品貨號：

BN41006R
中文名稱：

囊泡對接蛋白p115抗體
英文名稱：

Rabbit anti-Vesicle docking protein p115 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41006R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Chicken,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41006R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Chicken,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱	Vesicle docking protein p115
中文名稱	囊泡對接蛋白p115抗體
別名	P115-RhoGEF General vesicular transport factor; General vesicular transport factor p115; P115; TAP; Transcytosis associated protein; VDP; Vesicle docking protein; USO1_HUMAN.
研究領域	免疫學信號轉導結合蛋白 G蛋白偶聯受體
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Chicken, Pig, Cow, Horse, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	108kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Vesicle docking protein p115:501-600/962
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	p115 (Vesicle docking protein p115) is a peripheral membrane protein that is located on the Golgi complex. p115 exists as a homodimer with two globular heads, an extended coiled-coil tail, followed by an acidic domain at the extreme C terminus. p115 is homologous to a yeast protein, Uso1p, which is required for ER to Golgi transport. p115 likely plays an important role in vesicle transportation from the ER to the cis-Golgi comparments. Function: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity. Subunit: Homodimer. Dimerizes by parallel association of the tails, resulting in an elongated structure with two globular head domains side by side, and a long rod-like tail structure (Probable). Interacts with MIF. Subcellular Location: Cytoplasm; cytosol. Golgi apparatus membrane. Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes. Post-translational modifications: Phosphorylated in a cell cycle-specific manner; phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane; phosphorylation promotes dissociation. Similarity: Belongs to the VDP/USO1/EDE1 family. Contains 10 ARM repeats. SWISS: O60763 Gene ID: 8615 Database links: Entrez Gene: 317724 Cow Entrez Gene: 8615 Human Entrez Gene: 56041 Mouse Entrez Gene: 56042 Rat Omim: 603344 Human SwissProt: P41541 Cow SwissProt: O60763 Human SwissProt: Q9Z1Z0 Mouse SwissProt: P41542 Rat Unigene: 292689 Human Unigene: 15868 Mouse Unigene: 4746 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.