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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>胚胎干細胞關鍵蛋白190抗體(N端)
      胚胎干細胞關鍵蛋白190抗體(N端)
      • 產品貨號:
        BN40969R
      • 中文名稱:
        胚胎干細胞關鍵蛋白190抗體(N端)
      • 英文名稱:
        Rabbit anti-Oct-4B/OCT4B-190 Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN40969R-100ul

        100ul

        ¥2360.00

        交叉反應:Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應用:WB,IHC-P,Flow-Cyt,ELISA

      • BN40969R-200ul

        200ul

        ¥3490.00

        交叉反應:Human,Mouse,Rat(predicted:Dog,Pig,Cow) 推薦應用:WB,IHC-P,Flow-Cyt,ELISA

      產品描述

      英文名稱Oct-4B/OCT4B-190
      中文名稱胚胎干細胞關鍵蛋白190抗體(N端)
      別    名Oct-4B; Oct4B; Oct 4B; Oct 4B-190; Oct4B-190; POU domain, class 5, transcription factor 1; Octamer-binding transcription factor 3; Oct-3; NF-A3; Otf-3; Otf3; POU5F1.  
      研究領域腫瘤  細胞生物  免疫學  干細胞  轉錄調節因子  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 Flow-Cyt=1μg /Test (石蠟切片需做抗原修復)
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量21/39kDa
      細胞定位細胞核 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human OCT4B-190:201-300/360 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq].

      SWISS:
      Q01860

      Gene ID:
      5460

      Database links:

      Entrez Gene: 5460 Human

      Entrez Gene: 18999 Mouse

      Entrez Gene: 294562 Rat

      Omim: 164177 Human

      SwissProt: Q01860 Human

      SwissProt: P20263 Mouse

      Unigene: 249184 Human

      Unigene: 632482 Human

      Unigene: 646545 Human

      Unigene: 17031 Mouse

      Unigene: 161748 Rat



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

      OCT4B-190蛋白能夠增強細胞在應激條件下抵抗凋亡的能力。OCT4基因在干細胞的增殖、分化、應激反應、凋亡過程等多個生物學過程中發揮著重要的作用。


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