親環蛋白（親環素）PPIG抗體

產品貨號：

BN40937R
中文名稱：

親環蛋白（親環素）PPIG抗體
英文名稱：

Rabbit anti-PPIG Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40937R-100ul

100ul

￥2360.00

交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,ELISA
BN40937R-200ul

200ul

￥3490.00

交叉反應：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,ELISA

產品描述

英文名稱	PPIG
中文名稱	親環蛋白（親環素）PPIG抗體
別名	CARS cyclophilin; CARS Cyp; CARS-cyclophilin; CARS-Cyp; CASP 10; CASP10; Clk associating RS cyclophilin; Clk-associating RS-cyclophilin; Cyclophilin G; CyclophilinG; CYP; MGC133241; Peptidyl prolyl cis trans isomerase G; Peptidyl prolyl isomerase G; Peptidyl-prolyl cis-trans isomerase G; Peptidyl-prolyl isomerase G; Peptidylprolyl isomerase G (cyclophilin G); Peptidylprolyl isomerase G; PPIase G; Ppig; PPIG_HUMAN; Rotamase G; RotamaseG; SCAF10; SR cyclophilin; SR cyp; SR related CTD associated factor 10; SR-cyclophilin; SR-cyp; SRcyp.
研究領域	細胞生物免疫學染色質和核信號信號轉導表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	89kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human PPIG:351-450/754
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	PPIG belongs to the the peptidyl-prolyl cis/trans isomerase protein family (PPIases). PPIases accelerate the folding of proteins. PPIG catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and is implicated in the folding, transport, and assembly of proteins. It is distributed in nuclear speckles, a nuclear compartment rich in splicing factors, and colocalizes with the splicing factors SC35 and pinin, suggesting a role in the regulation of pre-mRNA splicing. Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. Subunit: Interacts with CLK1, PNN and with the phosphorylated C-terminal domain of RNA polymerase II. Subcellular Location: Nucleus matrix. Nucleus speckle. Note=Colocalizes with RNA splicing factors at nuclear speckles. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 PPIase cyclophilin-type domain. SWISS: Q13427 Gene ID: 9360 Database links: Entrez Gene: 9360 Human Entrez Gene: 228005 Mouse Entrez Gene: 83624 Rat Omim: 606093 Human SwissProt: Q13427 Human SwissProt: A2AR02 Mouse SwissProt: O55035 Rat Unigene: 727580 Human Unigene: 11815 Mouse Unigene: 474951 Mouse Unigene: 10898 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肽基脯氨?；樂串悩嬅?，廣泛存在于各種組織和器官。根據對免疫抑制劑的敏感性，分屬三個獨立的家族：親環蛋白PPIG、FK506結合蛋白和細蛋白。能夠加速自身折疊和體內新生肽鏈折疊及變性蛋白質的體外折疊，主要分布于內質網。