原癌基因M-ras抗體

產品貨號：

BN40731R
中文名稱：

原癌基因M-ras抗體
英文名稱：

Rabbit anti-MRas Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40731R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat 推薦應用：WB
BN40731R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat 推薦應用：WB

產品描述

英文名稱	MRas
中文名稱	原癌基因M-ras抗體
別名	M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas.
研究領域	腫瘤細胞生物免疫學細胞凋亡轉錄調節因子
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat,
產品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	23kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from mouse MRas:201-259/259
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling. Function: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Tissue Specificity: Expression highly restricted to the brain and heart. Similarity: Belongs to the small GTPase superfamily. Ras family. SWISS: O08989 Gene ID: 17532 Database links: Entrez Gene: 22808 Human Entrez Gene: 17532 Mouse Entrez Gene: 25482 Rat Omim: 608435 Human SwissProt: O14807 Human SwissProt: O08989 Mouse SwissProt: P97538 Rat Unigene: 527021 Human Unigene: 2045 Mouse Unigene: 10641 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. M-ras癌變基因的表達產物Ras蛋白存在于多數腫瘤之中，目前是腫瘤研究較重要的蛋白之一.