GDNF家族受體α-1抗體

產品貨號：

BN40686R
中文名稱：

GDNF家族受體α-1抗體
英文名稱：

Rabbit anti-GDNFRA Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40686R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推薦應用：WB
BN40686R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Rabbit) 推薦應用：WB

產品描述

英文名稱	GDNFRA
中文名稱	GDNF家族受體α-1抗體
別名	GDNF Receptor alpha 1; GFRa-1; GFR alpha; GDNFR alpha; TmR1; GFR alpha-1; RETL1; RET ligand 1; TGF-beta related neurotrophic factor receptor-1; AU042498; DKFZp313E1012; DKFZp686J0156; FLJ10561; FLJ31546; GDNFR; Gdnfr alpha; GFR-ALPHA-1; GFRA1; GRFA1; LOC143381; MGC23045; Ret; RET1L; RETL1; TRNR1; GFRA1_HUMAN; GDNF family receptor alpha-1; GDNF receptor alpha-1; GDNFR-alpha-1; TGF-beta-related neurotrophic factor receptor 1.
研究領域	免疫學神經生物學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Rabbit, )
產品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	44kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GDNFRA:81-180/465
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] Function: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Subunit: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Similarity: Belongs to the GDNFR family. SWISS: P56159 Gene ID: 2674 Database links: Entrez Gene: 2674 Human Entrez Gene: 14585 Mouse Entrez Gene: 25454 Rat Omim: 601496 Human SwissProt: P56159 Human SwissProt: P97785 Mouse SwissProt: Q62997 Rat Unigene: 591913 Human Unigene: 88489 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GFRα-1是由68個氨基酸組成的蛋白，廣泛表達于中樞神經系統和外周器官?；钚詠唵挝挥蓛蓚€GFRα-1分子中間由二硫鍵連接而成的復合物。屬于GDNFR 家族成員。