清道夫受體B1+B2抗體

產品貨號：

BN40489R
中文名稱：

清道夫受體B1+B2抗體
英文名稱：

Rabbit anti-Scavenger Receptor BI + BII Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40489R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,ELISA
BN40489R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,ELISA

產品描述

英文名稱	Scavenger Receptor BI + BII
中文名稱	清道夫受體B1+B2抗體
別名	85 kDa lysosomal membrane sialoglycoprotein; CD36 and LIMPII Analogous 1; CD36L1; CD36L2; CLA1; HLGP85; LGP85; LIMP II; Lysosome membrane protein II; MGC138242; SCARB1; SCARB2; Scavenger receptor class B member 2; Scavenger Receptor Class B Type I; SRBI; SRBII.
研究領域	腫瘤心血管細胞生物信號轉導細胞膜受體新陳代謝
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	61kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Scavenger Receptor BI + BII:31-130/552
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] Function: High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells. Subcellular Location: Lysosome; lysosomal membrane; multi-pass membrane protein. SWISS: Q14108 Gene ID: 949 Database links: Entrez Gene: 949 Human Entrez Gene: 950 Human Entrez Gene: 12492 Mouse Entrez Gene: 20778 Mouse Entrez Gene: 117106 Rat Entrez Gene: 25073 Rat Omim: 601040 Human Omim: 602257 Human SwissProt: Q14108 Human SwissProt: Q8WTV0 Human SwissProt: O35114 Mouse SwissProt: Q61009 Mouse SwissProt: P27615 Rat SwissProt: P97943 Rat Unigene: 298813 Human Unigene: 349656 Human Unigene: 592984 Human Unigene: 282242 Mouse Unigene: 297964 Mouse Unigene: 399507 Mouse Unigene: 410528 Mouse Unigene: 3957 Rat Unigene: 88169 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.