G蛋白通路抑制物蛋白2抗體

產品貨號：

BN40456R
中文名稱：

G蛋白通路抑制物蛋白2抗體
英文名稱：

Rabbit anti-GPS2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40456R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40456R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	GPS2
中文名稱	G蛋白通路抑制物蛋白2抗體
別名	AMF-1; G protein pathway suppressor 2; GPS-2; GPS2; MGC104294; MGC119287; MGC119288; MGC119289; GPS2_HUMAN.
研究領域	細胞生物免疫學染色質和核信號信號轉導 G蛋白偶聯受體表觀遺傳學 G蛋白信號
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/test ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	37kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GPS2:1-100/327
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008] Function: Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. Subunit: Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Tissue Specificity: Widely expressed. SWISS: Q13227 Gene ID: 2874 Database links: Entrez Gene: 2874 Human SwissProt: Q13227 Human Unigene: 438219 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.