氧化還原酶GlyR1/核蛋白60抗體

產品貨號：

BN40422R
中文名稱：

氧化還原酶GlyR1/核蛋白60抗體
英文名稱：

Rabbit anti-GLYR1 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40422R-100ul

100ul

￥2360.00

交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Monkey) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40422R-200ul

200ul

￥3490.00

交叉反應：Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Monkey) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	GLYR1
中文名稱	氧化還原酶GlyR1/核蛋白60抗體
別名	3 hydroxyisobutyrate dehydrogenase like protein; 3-hydroxyisobutyrate dehydrogenase-like protein; BM045; Cytokine like nuclear factor n pac; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; GLYR1; GLYR1_HUMAN; HIBDL; N-PAC; NP60; Nuclear protein 60 kDa; Nuclear protein NP60; Nuclear protein of 60 kDa; Putative oxidoreductase GLYR1.
研究領域	細胞生物信號轉導激酶和磷酸酶表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Monkey, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	61kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human GLYR1/NP60:21-120/553
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	NP60 is a 553 amino acid nuclear protein that regulates the phosphorylation and activation of p38 alpha in response to stress. There are five isoforms of NP60 that are produced as a result of alternative splicing events. Function: May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3). Subunit: Interacts with MAPK14. Subcellular Location: Nucleus. Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family. NP60 subfamily. Contains 1 A.T hook DNA-binding domain. Contains 1 PWWP domain. SWISS: Q49A26 Gene ID: 84656 Database links: Entrez Gene: 84656 Human Entrez Gene: 74022 Mouse Entrez Gene: 360477 Rat Omim: 610660 Human SwissProt: Q49A26 Human SwissProt: Q922P9 Mouse SwissProt: Q5RKH0 Rat Unigene: 387255 Human Unigene: 21652 Mouse Unigene: 2639 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.