冷休克蛋白DBPA抗體

產品貨號：

BN40401R
中文名稱：

冷休克蛋白DBPA抗體
英文名稱：

Rabbit anti-DBPA Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40401R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40401R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	DBPA
中文名稱	冷休克蛋白DBPA抗體
別名	Cold shock domain containing protein A; Cold shock domain-containing protein A; csdA; CSDA1; DBPA; DNA binding protein A; DNA-binding protein A; Single strand DNA binding protein NF GMB; Single-strand DNA-binding protein NF-GMB; ZO 1 associated nucleic acid binding protein; ZO1 associated nucleic acid binding protein; ZONAB; YBOX3_HUMAN; Y-box-binding protein 3.
研究領域	細胞生物信號轉導細胞周期蛋白轉錄調節因子表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	40kDa
細胞定位	細胞核細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human DBPA/CSDA1:165-270/372
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	CSDA is a 372 amino acid nuclear and cytoplasmic protein that is highly expressed in skeletal muscle and heart. Containing one CSD (cold-shock) domain, CSDA is thought to bind to GM-CSF promoter, full length mRNA and to short RNA sequences containing a specific consensus site. CSDA is suggested to have a role in translation repression and is found in a mRNP complex with MSY2. MSY2 belongs to the Y-box family of multifunctional proteins that regulate both transcription and translation. CSDA participates in promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA). CSDA is regarded to be an important component of the mechanisms that sense epithelial density and in regulating the switch between proliferation and differentiation through complex transcriptional networks. Function: Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highly expressed in skeletal muscle and heart. Similarity: Contains 1 CSD (cold-shock) domain. SWISS: P16989 Gene ID: 8531 Database links: Entrez Gene: 8531 Human Entrez Gene: 56449 Mouse Entrez Gene: 83807 Rat Omim: 603437 Human SwissProt: P16989 Human SwissProt: Q61478 Mouse SwissProt: Q68G78 Mouse SwissProt: Q8BPG0 Mouse SwissProt: Q9JKB3 Mouse SwissProt: Q3KRC7 Rat SwissProt: Q62764 Rat Unigene: 221889 Human Unigene: 299604 Mouse Unigene: 458000 Mouse Unigene: 3306 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.