GCNT1葡萄糖轉移酶抗體

產品貨號：

BN40361R
中文名稱：

GCNT1葡萄糖轉移酶抗體
英文名稱：

Rabbit anti-GCNT1 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40361R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40361R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Dog,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	GCNT1
中文名稱	GCNT1葡萄糖轉移酶抗體
別名	3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase; Beta-1; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; C2GNT; C2GNT L; C2GNT1; C2GnTL; Core 2 branching enzyme; Core 2 GNT; Core 2-branching enzyme; Core2 GlcNAc transferase; Core2-GlcNAc-transferase; GCNT 1; GCNT 1; GCNT1; GCNT1_HUMAN; glucosaminyl (N-acetyl) transferase 1 core 2; NACGT2.
研究領域	腫瘤細胞生物信號轉導糖蛋白新陳代謝
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Cow, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	50kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from Human GCNT1:201-260/428
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins. Function: Forms critical branches in O-glycans. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Highly expressed in activated T-lymphocytes and myeloid cells. Similarity: Belongs to the glycosyltransferase 14 family. SWISS: Q02742 Gene ID: 2650 Database links: Entrez Gene: 2650 Human Entrez Gene: 14537 Mouse Omim: 600391 Human SwissProt: Q02742 Human SwissProt: Q09324 Mouse Unigene: 521568 Human Unigene: 244825 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.