指甲髕骨綜合征相關蛋白NPS1抗體

產品貨號：

BN40328R
中文名稱：

指甲髕骨綜合征相關蛋白NPS1抗體
英文名稱：

Rabbit anti-LMX1b Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40328R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40328R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	LMX1b
中文名稱	指甲髕骨綜合征相關蛋白NPS1抗體
別名	LIM homeo box transcription factor 1 beta; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1-beta; LIM-homeobox protein 1.2; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX 1.2; LMX-1.2; LMX1.2; LMX1B; LMX1B_HUMAN; NPS 1; NPS1.
研究領域	細胞生物發育生物學神經生物學表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	42kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human LMX1b/NPS1:111-210/379
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010] Function: Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Subcellular Location: Nucleus. Tissue Specificity: Expressed in most tissues. Highest levels in testis, thyroid, duodenum, skeletal muscle, and pancreatic islets. DISEASE: Defects in LMX1B are the cause of nail-patella syndrome (NPS) [MIM:161200]; also known as onychoosteodysplasia. NPS is a disease that cause abnormal skeletal patterning and renal dysplasia. Similarity: Contains 1 homeobox DNA-binding domain. Contains 2 LIM zinc-binding domains. SWISS: O60663 Gene ID: 4010 Database links: Entrez Gene: 4010 Human Entrez Gene: 16917 Mouse Entrez Gene: 114501 Rat GenBank: U77457.1 Human Omim: 602575 Human SwissProt: O60663 Human SwissProt: O88609 Mouse Unigene: 129133 Human Unigene: 39825 Mouse Unigene: 92364 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.