生長激素釋放激素同源盒蛋白1抗體

產品貨號：

BN40318R
中文名稱：

生長激素釋放激素同源盒蛋白1抗體
英文名稱：

Rabbit anti-Gsh1 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40318R-100ul

100ul

￥2360.00

交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40318R-200ul

200ul

￥3490.00

交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	Gsh1
中文名稱	生長激素釋放激素同源盒蛋白1抗體
別名	GS homeo box protein 1; GS homeobox 1; GSH1; GSX1; GSX1_HUMAN; Homeobox protein GSH-1 ; Homeobox protein Gsh1.
研究領域	細胞生物神經生物學信號轉導干細胞表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, (predicted: Human, Rat, Dog, Pig, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	28kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Gsh1:165-264/264
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Growth hormone-releasing hormone (GHRH) stimulates secretion and synthesis of growth hormone (GH), causes somatotroph proliferation and may have direct actions in fetal/placental development, reproduction and immune function. It exerts its action through high-affinity GHRH receptors present in the anterior pituitary. GSH-1 (GS homeobox 1) is a 264 amino acid hypothalamic nuclear protein that functions as a transcription factor responsible for maintaining GHRH expression as well as playing an important role in pituitary development. Coexpression of CBP leads to significantly enhanced GSH-1-induced GHRH expression, which suggest that CBP may function as a co-activator. Knockdown of GSH-1 mRNA in mice causes a dwarf phenotype, which suggests that certain cases of familial dwarfism may be caused by a mutation of the GSH-1 gene. Function: Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the transcription of the GHRH gene. Plays an important role in pituitary development. Subcellular Location: Nucleus. Similarity: Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. SWISS: Q9H4S2 Gene ID: 219409 Database links: Entrez Gene: 219409 Human Entrez Gene: 14842 Mouse Entrez Gene: 288457 Rat SwissProt: Q9H4S2 Human SwissProt: P31315 Mouse Unigene: 351785 Human Unigene: 4797 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications