低密度脂蛋白受體5樣蛋白抗體

產品貨號：

BN40315R
中文名稱：

低密度脂蛋白受體5樣蛋白抗體
英文名稱：

Rabbit anti-LRP5L Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40315R-100ul

100ul

￥2360.00

交叉反應：Human(predicted:Mouse,Rat,Chicken,Sheep) 推薦應用：WB,ELISA
BN40315R-200ul

200ul

￥3490.00

交叉反應：Human(predicted:Mouse,Rat,Chicken,Sheep) 推薦應用：WB,ELISA

產品描述

英文名稱	LRP5L
中文名稱	低密度脂蛋白受體5樣蛋白抗體
別名	Low-density lipoprotein receptor-related protein 5-like protein; LRP-5-like; LRP5L; GP330; LRP5L_HUMAN.
研究領域	細胞生物發育生物學細胞周期蛋白轉錄調節因子表觀遺傳學細胞膜蛋白
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, (predicted: Mouse, Rat, Chicken, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	28kDa
細胞定位	細胞核細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human LRP5L:101-200/252
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing. Similarity: Contains 5 LDL-receptor class B repeats. SWISS: A4QPB2 Gene ID: 91355 Database links: Entrez Gene: 91355 Human SwissProt: A4QPB2 Human Unigene: 634058 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.