卵黃狀黃斑病蛋白4抗體

產品貨號：

BN40279R
中文名稱：

卵黃狀黃斑病蛋白4抗體
英文名稱：

Rabbit anti-Bestrophin 4 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN40279R-100ul

100ul

￥2360.00

交叉反應：Human(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40279R-200ul

200ul

￥3490.00

交叉反應：Human(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱	Bestrophin 4
中文名稱	卵黃狀黃斑病蛋白4抗體
別名	BEST 4; BEST4; BEST-4; Bestrophin 4; Bestrophin4; Bestrophin-4; Vitelliform macular dystrophy 2 like 2; Vitelliform macular dystrophy 2 like protein 2; VMD2L2; BEST4_HUMAN.
研究領域	腫瘤信號轉導通道蛋白
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	53kDa
細胞定位	細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Bestrophin 4:151-250/473 <Extracellular>
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina. Function: Forms calcium-sensitive chloride channels. Permeable to bicarbonate. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly found in colon and the weakly in fetal brain, spinal cord, retina, lung, trachea, testis and placenta. Similarity: Belongs to the bestrophin family. SWISS: Q9C0D5 Gene ID: 266675 Database links: Entrez Gene: 510542 Cow Entrez Gene: 482521 Dog Entrez Gene: 100052813 Horse Entrez Gene: 266675 Human Entrez Gene: 100345949 Rabbit Entrez Gene: 689103 Rat Omim: 607336 Human SwissProt: Q8NFU0 Human Unigene: 302513 Human Unigene: 84672 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.