促甲狀腺素釋放激素抗體

產品貨號：

BN41802R
中文名稱：

促甲狀腺素釋放激素抗體
英文名稱：

Rabbit anti-TRH/Prothyroliberin Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41802R-50ul

50ul

￥1486.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Horse,Rabbit) 推薦應用：WB
BN41802R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Horse,Rabbit) 推薦應用：WB
BN41802R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Horse,Rabbit) 推薦應用：WB

產品描述

英文名稱	TRH/Prothyroliberin
中文名稱	促甲狀腺素釋放激素抗體
別名	Thyrotropin releasing hormone; Protirelin; Thyroliberin [Precursor]; Thyroliberin; Thyrotropin releasing factor; TRF; TRH; TRH_HUMAN; TSH releasing factor; Prothyroliberin.
研究領域	腫瘤神經生物學信號轉導生長因子和激素內分泌病
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Dog, Pig, Horse, Rabbit, )
產品應用	WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	24kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human TRH/Prothyroliberin:131-240/242
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]. Function: Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets. Subcellular Location: Secreted Tissue Specificity: Hypothalamus. Expressed in the hair follicle epithelium (at protein level). Similarity: Belongs to the TRH family. SWISS: P20396 Gene ID: 7200 Database links: Entrez Gene: 7200 Human Entrez Gene: 22044 Mouse Entrez Gene: 25569 Rat Omim: 275120 Human SwissProt: P20396 Human SwissProt: Q62361 Mouse SwissProt: P01150 Rat Unigene: 1363 Mouse Unigene: 22 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 促甲狀腺激素釋放激素(TRH)是下丘腦合成及分泌的一種下丘腦激素，它可以促進垂體促甲狀腺激素的合成與分泌。促甲狀腺激素釋放激素的合成及分泌可以受血液中甲狀腺激素的調節。血液中甲狀腺激素增高(甲亢)可以抑制下丘腦促甲狀腺激素釋放激素(TRH)的生成，繼而使垂體促甲狀腺激素生成減少，甲狀腺激素增高也可以直接抑制垂體促甲狀腺激素的生成。血液中甲狀腺激素減少(甲低)可以興奮下丘腦促甲狀腺激素釋放激素(TRH)，繼而引起垂體促甲狀腺激素生成增加，甲狀腺激素減少還可以直接興奮垂體促甲狀腺激素的生成。