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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>β-酪蛋白抗體
      β-酪蛋白抗體
      • 產品貨號:
        BN41610R
      • 中文名稱:
        β-酪蛋白抗體
      • 英文名稱:
        Rabbit anti-Beta-casein Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN41610R-50ul

        50ul

        ¥1486.00

        交叉反應:Human,Cow,Goat(predicted:Sheep) 推薦應用:WB,ELISA

      • BN41610R-100ul

        100ul

        ¥2360.00

        交叉反應:Human,Cow,Goat(predicted:Sheep) 推薦應用:WB,ELISA

      • BN41610R-200ul

        200ul

        ¥3490.00

        交叉反應:Human,Cow,Goat(predicted:Sheep) 推薦應用:WB,ELISA

      產品描述

      英文名稱Beta-casein
      中文名稱β-酪蛋白抗體
      別    名Beta-casein; Casoparan; Antioxidant peptide; Casohypotensin; CASB; CASB_BOVIN; Casein beta; CSN 2; Csn2; CASB_BOVIN.  
      研究領域細胞生物  免疫學  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Human, Cow, Goat,  (predicted: Sheep, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量24kDa
      細胞定位分泌型蛋白 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from cow Beta-casein:16-100/224 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹Milk proteins are crucial for the development of all newborn mammals and caseins constitute the major proteins in mammalian milk. b- and k-caseins are the only caseins present in human milk. The b-casein/k-casein ratio is higher in colostrum than in transitional and mature milk and is related to a better digestibility of colostrum casein micelles by the neonate during the first days of life. Human b-casein-encoding gene (Bca) contains a highly phosphorylated site, which is responsible for the calcium-binding capacity of b-casein. A common set of transcription factors are required for the expression of b-casein. Multiple binding sites for Stat5, C/EBPb (CCAAT/enchancer-binding protein) and several half-sites for glucocorticoid receptor (GR) are identified in the distal human enhancer of the b-casein gene. b-casein gene transcription is regulated primarily by a composite response element (CoRE), which integrates signaling from the lactogenic hormones PRL, insulin and hydrocortisone in mammary epithelial cells. NFkB functions as a negative regulator of b-casein gene expression during pregnancy by interfering with Stat5 tyrosine phosphorylation

      Function:
      Important role in determination of the surface properties of the casein micelles.
      Casoparan acts as a macrophage activator, increasing the phagocytic activity of macrophages and peroxide release from macrophages. It also acts as a bradykinin-potentiating peptide.
      Casohypotensin acts as a bradykinin-potentiating peptide. Induces hypotension in rats. Acts as a strong competitive inhibitor of endo-oligopeptidase A.
      Antioxidant peptide has antioxidant activity.

      Subcellular Location:
      Secreted.

      Tissue Specificity:
      Mammary gland specific. Secreted in milk.

      Similarity:
      Belongs to the beta-casein family.

      SWISS:
      P11839

      Gene ID:
      443391

      Database links:

      Entrez Gene: 1447 Human

      Entrez Gene: 281099 Bovin

      Entrez Gene: 443391 Sheep

      Omim: 115460 Human

      SwissProt: P05814 Human

      SwissProt: P02666 Bovin

      Unigene: 2242 Human



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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