脊髓灰質炎病毒受體相關蛋白4抗體

產品貨號：

BN41609R
中文名稱：

脊髓灰質炎病毒受體相關蛋白4抗體
英文名稱：

Rabbit anti-Nectin 4 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41609R-50ul

50ul

￥1486.00

交叉反應：Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用：WB,ELISA
BN41609R-100ul

100ul

￥2360.00

交叉反應：Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用：WB,ELISA
BN41609R-200ul

200ul

￥3490.00

交叉反應：Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用：WB,ELISA

產品描述

英文名稱	Nectin 4
中文名稱	脊髓灰質炎病毒受體相關蛋白4抗體
別名	Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4; DKFZp686K05193; EDSS1; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; pvrl4; PVRL4_HUMAN.
研究領域	腫瘤細胞生物免疫學細菌及病毒
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Pig, Cow, Horse, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	53kDa
細胞定位	細胞膜分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Nectin 4:151-250/510
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. Function: Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus. Subcellular Location: Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction. Processed poliovirus receptor-related protein 4: Secreted. Tissue Specificity: Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. Similarity: Belongs to the nectin family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. SWISS: Q96NY8 Gene ID: 81607 Database links: Entrez Gene: 81607 Human Entrez Gene: 71740 Mouse Entrez Gene: 498281 Rat Omim: 609607 Human SwissProt: Q5E9Z9 Cow SwissProt: Q96NY8 Human SwissProt: Q8R007 Mouse Unigene: 492490 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.