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    2. 最近搜索:細胞培養 微生物學 分子生物 生物化學
      首頁>>免疫學>>一抗>>脊髓灰質炎病毒受體相關蛋白4抗體
      脊髓灰質炎病毒受體相關蛋白4抗體
      • 產品貨號:
        BN41609R
      • 中文名稱:
        脊髓灰質炎病毒受體相關蛋白4抗體
      • 英文名稱:
        Rabbit anti-Nectin 4 Polyclonal antibody
      • 品牌:
        Biorigin
      • 貨號

        產品規格

        售價

        備注

      • BN41609R-50ul

        50ul

        ¥1486.00

        交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

      • BN41609R-100ul

        100ul

        ¥2360.00

        交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

      • BN41609R-200ul

        200ul

        ¥3490.00

        交叉反應:Mouse,Human(predicted:Rabbit,Horse,Cow,Pig,Rat) 推薦應用:WB,ELISA

      產品描述

      英文名稱Nectin 4
      中文名稱脊髓灰質炎病毒受體相關蛋白4抗體
      別    名Ig superfamily receptor LNIR; Nectin 4; poliovirus receptor-related 4; PRR4; poliovirus receptor related 4; DKFZp686K05193; EDSS1; Nectin-4; poliovirus receptor-related 4; Processed poliovirus receptor-related protein 4; pvrl4; PVRL4_HUMAN.  
      研究領域腫瘤  細胞生物  免疫學  細菌及病毒  
      抗體來源Rabbit
      克隆類型Polyclonal
      交叉反應Human, Mouse,  (predicted: Rat, Pig, Cow, Horse, Rabbit, )
      產品應用WB=1:500-2000 ELISA=1:5000-10000 
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量53kDa
      細胞定位細胞膜 分泌型蛋白 
      性    狀Liquid
      濃    度1mg/ml
      免 疫 原KLH conjugated synthetic peptide derived from human Nectin 4:151-250/510 
      亞    型IgG
      純化方法affinity purified by Protein A
      儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
      PubMedPubMed
      產品介紹This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

      Function:
      Self-associates. Interacts via its Ig-like V-type domain with PVRL1/nectin-1 Ig-like V-type domain. Interacts via its C-terminus with MLLT4. Binds to Measles virus protein H and acts as a receptor for this virus.

      Subcellular Location:
      Cell membrane; Single-pass type I membrane protein (Potential). Cell junction, adherens junction. Processed poliovirus receptor-related protein 4: Secreted.

      Tissue Specificity:
      Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.

      Similarity:
      Belongs to the nectin family.
      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

      SWISS:
      Q96NY8

      Gene ID:
      81607

      Database links:

      Entrez Gene: 81607 Human

      Entrez Gene: 71740 Mouse

      Entrez Gene: 498281 Rat

      Omim: 609607 Human

      SwissProt: Q5E9Z9 Cow

      SwissProt: Q96NY8 Human

      SwissProt: Q8R007 Mouse

      Unigene: 492490 Human



      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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