線粒體鈉/氫交換蛋白質2抗體

產品貨號：

BN41401R
中文名稱：

線粒體鈉/氫交換蛋白質2抗體
英文名稱：

Rabbit anti-NHEDC2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41401R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Rabbit) 推薦應用：WB,ELISA
BN41401R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse(predicted:Rat,Dog,Rabbit) 推薦應用：WB,ELISA

產品描述

英文名稱	NHEDC2
中文名稱	線粒體鈉/氫交換蛋白質2抗體
別名	NHA2; Mitochondrial Na(+)/H(+) exchanger NHA2; Mitochondrial sodium/hydrogen exchanger NHA2; Na(+)/H(+) exchanger like domain containing protein 2; Na+/H+ exchanger domain containing 2; NHE domain containing protein 2; NHE10; NHEDC 2; Sodium/hydrogen exchanger like domain containing protein 2; SL9B2_HUMAN.
研究領域	細胞生物信號轉導細胞周期蛋白細胞分化細胞骨架細胞外基質
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, (predicted: Rat, Dog, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	58kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human NHEDC2:151-250/537
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events. Function: Electroneutral exchange of protons for Na(+) and Li(+)across the inner mitochondrial membrane. Contributes to theorganellar volume homeostasis. Required for osteoclastdifferentiation and bone resorption activity (By similarity). Subcellular Location: Mitochondrion membrane; Multi-pass membraneprotein (By similarity). Tissue Specificity: Detected in red blood cells (at proteinlevel). Similarity: Belongs to the monovalent cation:proton antiporter 1(CPA1) transporter (TC 2.A.36) family. SWISS: Q86UD5 Gene ID: 133308 Database links: Entrez Gene: 133308 Human Entrez Gene: 97086 Mouse Entrez Gene: 365946 Rat Omim: 611789 Human SwissProt: Q86UD5 Human SwissProt: Q5BKR2 Mouse Unigene: 546482 Human Unigene: 441764 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.