葡萄糖神經酰胺合成酶抗體

產品貨號：

BN41340R
中文名稱：

葡萄糖神經酰胺合成酶抗體
英文名稱：

Rabbit anti-Ceramide glucosyltransferase Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41340R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,ELISA
BN41340R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) 推薦應用：WB,IHC-P,ELISA

產品描述

英文名稱	Ceramide glucosyltransferase
中文名稱	葡萄糖神經酰胺合成酶抗體
別名	CEGT_HUMAN; UGCG; GCS; GLCT 1; GLCT-1; GLCT1; Glucosylceramide synthase; UDP glucose ceramide glucosyltransferase; UDP glucose N acylsphingosine D glucosyltransferase; UDP-glucose ceramide glucosyltransferase; UDP-glucose:N-acylsphingosine D-glucosyltransferase; Ugcg.
研究領域	腫瘤細胞生物細胞凋亡細胞分化
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Human, Mouse, Rat, (predicted: Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	45kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human UGCG:31-98/394
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types. Function: Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase". Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Found in all tissues examined. Similarity: Belongs to the glycosyltransferase 2 family. SWISS: Q16739 Gene ID: 7357 Database links: Entrez Gene: 7357 Human Entrez Gene: 22234 Mouse Entrez Gene: 83626 Rat Omim: 602874 Human SwissProt: Q16739 Human SwissProt: O88693 Mouse SwissProt: Q9R0E0 Rat Unigene: 304249 Human Unigene: 593014 Human Unigene: 198803 Mouse Unigene: 24091 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.