絲氨酸/蘇氨酸蛋白激酶Nek7抗體

產品貨號：

BN41271R
中文名稱：

絲氨酸/蘇氨酸蛋白激酶Nek7抗體
英文名稱：

Rabbit anti-NEK7 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41271R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat(predicted:Human,Chicken,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA
BN41271R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat(predicted:Human,Chicken,Pig,Cow,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產品描述

英文名稱	NEK7
中文名稱	絲氨酸/蘇氨酸蛋白激酶Nek7抗體
別名	NEK7; NEK7_HUMAN; Never in mitosis A-related kinase 7; Never in mitosis gene a-related kinase 7; NIMA (never in mitosis gene a) related kinase 7; NIMA (never in mitosis gene a)-related expressed kinase 7; NimA related protein kinase 7; NIMA-related kinase 7; NimA-related protein kinase 7; Serine/threonine-protein kinase Nek7.
研究領域	細胞生物信號轉導激酶和磷酸酶細胞分化
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Chicken, Pig, Cow, Rabbit, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	35kDa
細胞定位	細胞核細胞漿
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human NEK7:101-200/302
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	Tissue specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. Function: Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. Phosphorylates RPS6KB1. Subunit: Monomer. Interacts with NEK9. Subcellular Location: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, centrosome. Note=Present at centrosome throughout the cell cycle. Also detected at spindle midzone of the anaphase cells and eventually concentrates at the midbody. Tissue Specificity: Highly expressed in lung, muscle, testis, brain, heart, liver, leukocyte and spleen. Lower expression in ovary, prostate and kidney. No expression seen in small intestine. Post-translational modifications: Phosphorylation at Ser-195 required for its activation. Similarity: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. Contains 1 protein kinase domain. SWISS: Q8TDX7 Gene ID: 140609 Database links: UniProtKB/Swiss-Prot: Q8TDX7.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.