腦特定蛋白Brn3B抗體

產品貨號：

BN41240R
中文名稱：

腦特定蛋白Brn3B抗體
英文名稱：

Rabbit anti-BRN3B Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41240R-100ul

100ul

￥2360.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA
BN41240R-200ul

200ul

￥3490.00

交叉反應：Mouse,Rat(predicted:Human,Dog,Pig,Cow,Horse,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,Flow-Cyt,ELISA

產品描述

英文名稱	BRN3B
中文名稱	腦特定蛋白Brn3B抗體
別名	BRN3B; class 4; transcription factor 2; Brain specific homeobox/POU domain protein 3B; Brain-3B; Brain-specific homeobox/POU domain protein 3B; Brn-3B; BRN3.2; Brn3b POU domain transcription factor; PO4F2_HUMAN; POU class 4 homeobox 2; POU domain; POU domain class 4 transcription factor 2; POU domain protein; POU4F2.
研究領域	細胞生物神經生物學信號轉導干細胞表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Horse, Sheep, )
產品應用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg /Test IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	41kDa
細胞定位	細胞核
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human BRN3B/POU4F2:301-400/409
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. Brn-1 and Brn-2 are class III POU (Pit-Oct-Unc) domain proteins, whereas Brn-3 is a class IV POU domain protein. Three Brn-3 proteins have been described and are designated Brn-3a, Brn-3b and Brn-3c. While Brn-3a and Brn-3c stimulate transcription, Brn-3b generally functions as a transcriptional repressor. However, Brn-3b, but not Brn-3a, has been shown to regulate the expression of the acetylcholine receptor. Interestingly, Brn-3a has two functional transactivating domains, one at the amino-terminus and one at the carboxy-terminus. Brn-2 is thought to be involved in smooth muscle cell development and differentiation. Function: Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Subcellular Location: Nucleus speckle. Tissue Specificity: Brain. Seems to be specific to the retina. Similarity: Belongs to the POU transcription factor family. Class-4 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain. SWISS: Q12837 Gene ID: 5458 Database links: UniProtKB/Swiss-Prot: Q12837.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.