內質網核信號轉導蛋白2抗體

產品貨號：

BN41233R
中文名稱：

內質網核信號轉導蛋白2抗體
英文名稱：

Rabbit anti-ERN2 Polyclonal antibody
品牌：

Biorigin

貨號

產品規格

售價

備注
BN41233R-100ul

100ul

￥2360.00

交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應用：Flow-Cyt,ELISA
BN41233R-200ul

200ul

￥3490.00

交叉反應：Mouse(predicted:Human,Rat,Dog,Pig,Cow,Sheep) 推薦應用：Flow-Cyt,ELISA

產品描述

英文名稱	ERN2
中文名稱	內質網核信號轉導蛋白2抗體
別名	IRE1b; Endoplasmic reticulum to nucleus signaling 2; ER to nucleus signalling 2; ERN 2; Ern1; hIRE2p; Inositol requiring 1 beta; Inositol requiring protein 2; Ire1; Ire1 beta; IRE1 S. cerevisiae homolog of; IRE2; Serine/threonine protein kinase/endoribonuclease IRE2; ERN2_HUMAN.
研究領域	細胞生物信號轉導細胞凋亡轉錄調節因子激酶和磷酸酶表觀遺傳學
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Sheep, )
產品應用	ELISA=1:5000-10000 Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	98kDa
細胞定位	細胞漿細胞膜
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ERN2:465-550/926
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	ERN2, endoplasmic reticulum to nucleus signaling 2, induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. It is pro-apoptotic and appears to play no role in the unfolded-protein response, unlike closely related proteins. Function: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Post-translational modifications: Autophosphorylated. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 KEN domain. Contains 1 protein kinase domain. SWISS: O75460 Gene ID: 10595 Database links: Entrez Gene: 10595 Human Entrez Gene: 26918 Mouse Omim: 604034 Human SwissProt: O75460 Human SwissProt: Q9EQY0 Mouse Unigene: 133982 Human Unigene: 20452 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.